In one of recently published research articles, we have investigated the empigenitcs of endothelial cells under low/high WSS of laminar flow in vitro. We found that the epigenetic landscape of endothelial cells reveals that low WSS is associated with a proapoptotic state, while high WSS is associated with a proliferative and proinflammatory state. Read the full article in the Journal of Cellular Physiology.
- 1.Rashad S, Han X, Saqr K, Tupin S, Ohta M, Niizuma K, et al. Epigenetic response of endothelial cells to different wall shear stress magnitudes: A report of new mechano‐miRNAs. J Cell Physiol [Internet]. 2020 Jan 8; Available from: http://dx.doi.org/10.1002/jcp.29436