Cerebrovascular Hemodynamics

The study of cerebrovascular hemodynamics is vital to better understand life-threatening conditions such as brain aneurysm and stroke. With a generous grant from the Science and Technology Development Fund (STDF, Egypt), I have co-founded the Research Center for Computational Neurovascular Hemodynamics (RCCNB) with Alexandria University in 2013. As a visiting associate professor with the Biomedical Flow Dynamics Laboratory (Ohta-Lab) of IFS, Tohoku University, I am working to investigate the role of turbulence in the development of cerebrovascular disease. I have authored the largest-to-date meta-analysis and review of CFD studies of intracranial aneurysm^​1​. In collaboration with the department of neurosurgical engineering and translational neuroscience of Tohoku University, I have co-discovered the hemodynamic causes of transient ischemic attack in early stage Moyamoya patients^​2​. In order to advance the CFD theory and practice in cerebrovascular hemodynamics, I have proposed the use of Modified Krieger Model (MKM) for the first time as a quasi-mechanistic representation of blood viscosity^​3​. I have also proposed the first in vivo evidence of the non-Newtonian physiologic behavior of intracranial blood flow^​4​.